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John J Turchi Selected Research

Replication Protein A

1/2022In Vivo Targeting Replication Protein A for Cancer Therapy.
11/2020Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer.
1/2015Chemical inhibitor targeting the replication protein A-DNA interaction increases the efficacy of Pt-based chemotherapy in lung and ovarian cancer.
3/2003RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions.

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John J Turchi Research Topics

Disease

19Neoplasms (Cancer)
01/2022 - 04/2004
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 07/2012
4Genomic Instability
01/2022 - 03/2003
4Ovarian Neoplasms (Ovarian Cancer)
11/2020 - 06/2013
4Xeroderma Pigmentosum (Kaposi's Disease)
10/2017 - 05/2002
3Lung Neoplasms (Lung Cancer)
01/2022 - 03/2014
2Carcinogenesis
01/2022 - 01/2008
2Hyperthermia
01/2022 - 01/2018
1Melanoma (Melanoma, Malignant)
01/2022
1Fanconi Anemia (Fanconi's Anemia)
11/2020
1Neoplasm Metastasis (Metastasis)
06/2013
1Ascites
06/2013
1Ataxia Telangiectasia (Louis Bar Syndrome)
03/2008
1Werner Syndrome (Werner's Syndrome)
01/2005
1Carcinoma (Carcinomatosis)
04/2004

Drug/Important Bio-Agent (IBA)

15DNA (Deoxyribonucleic Acid)IBA
01/2022 - 05/2002
10Proteins (Proteins, Gene)FDA Link
07/2021 - 05/2002
7PlatinumIBA
11/2020 - 04/2004
5Pharmaceutical PreparationsIBA
01/2022 - 03/2014
4Replication Protein AIBA
01/2022 - 03/2003
4Cisplatin (Platino)FDA LinkGeneric
04/2016 - 05/2005
2DiaminesIBA
01/2022 - 01/2018
21,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
01/2022 - 03/2008
2Antineoplastic Agents (Antineoplastics)IBA
01/2022 - 06/2020
2DNA AdductsIBA
12/2014 - 02/2010
2Phosphotransferases (Kinase)IBA
03/2014 - 03/2008
2Protein Glutamine gamma Glutamyltransferase 2IBA
06/2013 - 04/2011
2EnzymesIBA
06/2013 - 06/2011
2DNA-Binding Proteins (DNA Binding Protein)IBA
10/2010 - 03/2003
1Biomarkers (Surrogate Marker)IBA
01/2022
1EnediynesIBA
01/2022
1Polycomb Repressive Complex 1IBA
11/2020
1ChromatinIBA
11/2020
1Lysine (L-Lysine)FDA Link
11/2020
1Transcription Factors (Transcription Factor)IBA
12/2014
1guadecitabineIBA
12/2014
1Losartan (Cozaar)FDA LinkGeneric
03/2014
1Erlotinib Hydrochloride (CP 358,774)FDA Link
03/2014
1AstemizoleIBA
03/2014
1ErbB Receptors (EGF Receptor)IBA
10/2013
1TransglutaminasesIBA
06/2013
1Flap EndonucleasesIBA
01/2005

Therapy/Procedure

11Therapeutics
01/2022 - 01/2008
4Drug Therapy (Chemotherapy)
11/2020 - 07/2012